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ISSN (Print) 1013-9052
EISSN 1658-3558

The Saudi Dental Journal,
P.O. Box 52500,
Riyadh 11563,
Kingdom of Saudi Arabia
Tel.
966-1-467-7328
Fax.
933-1-467-7308 /
966-1-467-7534
Email
saudidj@ksu.edu.sa

Variations of some salivary antimicrobial factors in different

disease states: A review

   

Najla S. Dar-Odeh*, BDS, FDS, RCS (Ed)
Mohammad Awni Al-Kayed**,BDS, PhD
Faculty of Dentistry, University of Jordan, Amman, Jordan

The antimicrobial properties of saliva had been recognized for a long time owing to their importance in the natural defense mechanism of the body, particularly in diseases that have local effects on the tissues of the oral cavity.  The immune and non-immune antimicrobial salivary factors have been measured in different disease states to observe the variations in their levels in an attempt to understand the pathogenesis of some systemic diseases and to formulate better lines of treatment particularly for diseases that are either difficult to cure or that are not treatable yet. The aim of this paper was to review the literature on some antimicrobial factors and their variations in some disease states and to understand the inter-relationship between the salivary antimicrobial factors and systemic disseases asffecting the oral cavity. In order to have a better understanding of the factors affecting salivary secretions, there has to be a more standardized approach for saliva collection and analysis, more so because of some differences between the composition of mixed saliva and that from the individual salivary glands
 
Saudi Dental Journal 2002;14(1):99-104.
 
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