Abdullah M. AlDosari*, BDS, MSD, PhD
Amjad H. Wyne**, BDS, BSc, MDS, FASDC
Enosakhare S. Akpata***,  BDS, MDS, FDSRCPS, FWACS
Nazeer B. Khan**, MSc, PhD
Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh, KSA

Sodium hypochlorite as an endodontic irrigant, poses problems of toxicity, odor and discoloration of operatory items. An equally effective, but safe irrigant is desirable.  The purpose of this study was to compare the anti-microbial activity of propolis with that of sodium hypochlorite in an in vitro root canal system. Forty-nine extracted human teeth with large carious lesions reaching the pulp were instrumented using step-back technique.  Propolis, sodium hypochlorite and saline were used as irrigants.  Microbiological samples were taken from the teeth immediately after accessing the canal, and after instrumentation and irrigation. The results of this study indicated that the propolis has antimicrobial activity equal to that of sodium hypochlorite.

Saudi Dental Journal 2003;15(2):100-103.